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Literature summary for 6.1.1.4 extracted from

  • Kerjan, P.; Cerini, C.; Semeriva, M.; Mirande, M.
    The multienzyme complex containing nine aminoacyl-tRNA synthetases is ubiquitous from Drosophila to mammals (1994), Biochim. Biophys. Acta, 1199, 293-297.
    View publication on PubMed
Search for more literature for 6.1.1.4

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1200000
-
 gel filtration, multienzyme complex Drosophila sp. (in: flies)

Organism

Organism UniProt Comment Textmining
Bacteria
-
-
-
Drosophila sp. (in: flies)
-
-
-
eukaryota
-
-
-
Mammalia
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Drosophila sp. (in: flies)

Storage Stability

Storage Stability Organism
-20°C Drosophila sp. (in: flies)

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-leucine + tRNALeu
-
 Mammalia AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
ATP + L-leucine + tRNALeu
-
 Bacteria AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
ATP + L-leucine + tRNALeu
-
 eukaryota AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
ATP + L-leucine + tRNALeu
-
 Drosophila sp. (in: flies) AMP + diphosphate + L-leucyl-tRNALeu
-
 ?

Subunits

Subunits Comment Organism
? prokaryotes and lower eukaryotes: the corresponding enzymes behave as free enzymes Bacteria
? prokaryotes and lower eukaryotes: the corresponding enzymes behave as free enzymes eukaryota
? the multienzyme complex is composed of 10 distinct polypeptides with MW ranging from 18000 to 165000 Drosophila sp. (in: flies)
? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp Mammalia
? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp eukaryota
? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp Drosophila sp. (in: flies)