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Literature summary for 6.1.1.23 extracted from

  • Min, B.; Kitabatake, M.; Polycarpo, C.; Pelaschier, J.; Raczniak, G.; Ruan, B.; Kobayashi, H.; Namgoong, S.; Soll, D.
    Protein synthesis in Escherichia coli with mischarged tRNA (2003), J. Bacteriol., 185, 3524-3526.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.23

Cloned(Commentary)

Cloned (Comment) Organism
Escherichia coli trypA34 missense mutant transformed with heterologous ND-aspS gene Chlamydia trachomatis
Escherichia coli trypA34 missense mutant transformed with heterologous ND-aspS gene Halobacterium salinarum
Escherichia coli trypA34 missense mutant transformed with heterologous ND-aspS gene Deinococcus radiodurans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + Asp + tRNAAsn Halobacterium salinarum while large amounts of Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase AMP + diphosphate + aspartyl-tRNAAsn
-
 ?
ATP + Asp + tRNAAsn Chlamydia trachomatis while large amounts pf Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase AMP + diphosphate + aspartyl-tRNAAsn
-
 ?
ATP + Asp + tRNAAsn Deinococcus radiodurans while large amounts pf Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase AMP + diphosphate + aspartyl-tRNAAsn
-
 ?

Organism

Organism UniProt Comment Textmining
Chlamydia trachomatis
-
-
-
Deinococcus radiodurans
-
-
-
Halobacterium salinarum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Asp + tRNAAsn while large amounts of Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase Halobacterium salinarum AMP + diphosphate + aspartyl-tRNAAsn
-
 ?
ATP + Asp + tRNAAsn while large amounts pf Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase Chlamydia trachomatis AMP + diphosphate + aspartyl-tRNAAsn
-
 ?
ATP + Asp + tRNAAsn while large amounts pf Asp-tRNAAsn are detrimental to Escherichia coli with trypA34 missense mutation, a smaller amount supports protein synthesis and allows the formation of up to 38% of the wild-type level of missense-suppressed tryptophan synthetase Deinococcus radiodurans AMP + diphosphate + aspartyl-tRNAAsn
-
 ?

Synonyms

Synonyms Comment Organism
ND-AspRS
-
 Chlamydia trachomatis
ND-AspRS
-
 Halobacterium salinarum
ND-AspRS
-
 Deinococcus radiodurans
nondiscriminating aspartyl-tRNA synthetase
-
 Chlamydia trachomatis
nondiscriminating aspartyl-tRNA synthetase
-
 Halobacterium salinarum
nondiscriminating aspartyl-tRNA synthetase
-
 Deinococcus radiodurans