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Literature summary for 6.1.1.2 extracted from

  • Vecchione, J.J.; Sello, J.K.
    Characterization of an inducible, antibiotic-resistant aminoacyl-tRNA synthetase gene in Streptomyces coelicolor (2008), J. Bacteriol., 190, 6253-6257.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
chuangxinmycin
-
Streptomyces coelicolor
hygromycin
-
Streptomyces coelicolor
indolmycin
-
Streptomyces coelicolor
serine hydroxamate
-
Streptomyces coelicolor

Protein Variants

Protein Variants Comment Organism
additional information a Streptomyces coelicolor TrpRS1 null mutant is constructed Streptomyces coelicolor
additional information a Streptomyces coelicolor TrpRS2 null mutant is constructed Streptomyces coelicolor

Inhibitors

Inhibitors Comment Organism Structure
indolmycin
-
Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-tryptophan + tRNATrp Streptomyces coelicolor
-
AMP + diphosphate + L-tryptophyl-tRNATrp
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor Q8CJX0
-
-
Streptomyces coelicolor Q9KZA7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-tryptophan + tRNATrp
-
Streptomyces coelicolor AMP + diphosphate + L-tryptophyl-tRNATrp
-
?

Synonyms

Synonyms Comment Organism
TrpRS1
-
Streptomyces coelicolor
TrpRS2
-
Streptomyces coelicolor
tryptophanyl-tRNA synthetase1
-
Streptomyces coelicolor
tryptophanyl-tRNA synthetase2
-
Streptomyces coelicolor

Cofactor

Cofactor Comment Organism Structure
ATP
-
Streptomyces coelicolor