Literature summary for 6.1.1.2 extracted from

Werner, R.G.; Thorpe, L.F.; Reuter, W.; Nierhaus, K.H.
Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligase (1976), Eur. J. Biochem., 68, 1-3.

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Inhibitors

Inhibitors	Comment	Organism	Structure
indolmycin	specifically inhibits enzyme	Escherichia coli
indolmycin	liver enzyme is affected much less	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-tryptophan + tRNATrp	-	Escherichia coli	AMP + diphosphate + L-tryptophan-tRNATrp	-	?
ATP + L-tryptophan + tRNATrp	-	Rattus norvegicus	AMP + diphosphate + L-tryptophan-tRNATrp	-	?

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Release 2023.1 (January 2023)