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Literature summary for 6.1.1.2 extracted from

  • Merkulova, T.; Kovaleva, G.; Kisselev, L.
    P1,P3-bis(5'-adenosyl)triphosphate (Ap3A) as a substrate and product of mammalian tryptophanyl-tRNA synthetase (1994), FEBS Lett., 350, 287-290.
    View publication on PubMed
Search for more literature for 6.1.1.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.22
-
 ATP aminoacylation Bos taurus
1
-
 P1,P3-bis(5'-adenosyl)triphosphate aminoacylation, ammonia Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-tryptophan + tRNATrp Bos taurus
-
 ?
-
 ?
additional information Bos taurus enzyme might by implicated in regulation of P1,P3-bis(5'-adenosyl)triphosphate/P1,P4-bis(5'-adenosyl)tetraphosphate ratio in the cell ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-tryptophan + tRNATrp
-
 Bos taurus AMP + diphosphate + L-tryptophan-tRNATrp
-
 ?
ATP + L-tryptophan + tRNATrp
-
 Bos taurus ?
-
 ?
L-tryptophan + ATP + ADP
-
 Bos taurus P1,P3-bis(5'-adenosyl)triphosphate + ?
-
 ?
additional information no P1,P4-bis(5'-adenosyl)tetraphosphate synthesis Bos taurus ?
-
 ?
additional information enzyme might by implicated in regulation of P1,P3-bis(5'-adenosyl)triphosphate/P1,P4-bis(5'-adenosyl)tetraphosphate ratio in the cell Bos taurus ?
-
 ?
P1,P3-bis(5'-adenosyl)triphosphate + L-tryptophan + tRNATrp
-
 Bos taurus ?
-
 ?