Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hemin | hemin induces a dimeric form of the enzyme that is thus rendered enzymatically dead as it is unable to recognize its cognate tRNAarg | Plasmodium falciparum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Plasmodium falciparum | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
69000 | - |
blue native PAGE | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-arginine + tRNAArg | Plasmodium falciparum | - |
AMP + diphosphate + L-arginyl-tRNAArg | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q8I5M2 | - |
- |
Purification (Comment) | Organism |
---|---|
affinity column chromatography, ion-exchange column chromatography, and Superdex 200 gel filtration | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-arginine + tRNAArg | - |
Plasmodium falciparum | AMP + diphosphate + L-arginyl-tRNAArg | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 69000, SDS-PAGE | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
Arginyl-tRNA synthetase | - |
Plasmodium falciparum |
RRS | - |
Plasmodium falciparum |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
43 | - |
melting temperature | Plasmodium falciparum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Plasmodium falciparum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.002 | - |
pH and temperature not specified in the publication | Plasmodium falciparum | hemin |