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Literature summary for 6.1.1.19 extracted from

  • Shen, Y.; Zhao, H.Y.; Wang, H.J.; Wang, W.L.; Zhang, L.Z.; Fu, R.
    Ischemic preconditioning inhibits over-expression of arginyl-tRNA synthetase gene Rars in ischemia-injured neurons (2016), J. Huazhong Univ. Sci. Technol. Med. Sci., 36, 554-557 .
    View publication on PubMed
Search for more literature for 6.1.1.19

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-arginine + tRNAArg Rattus norvegicus
-
 AMP + diphosphate + L-arginyl-tRNAArg
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P40329
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-arginine + tRNAArg
-
 Rattus norvegicus AMP + diphosphate + L-arginyl-tRNAArg
-
 ?

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
Arginyl-tRNA synthetase
-
 Rattus norvegicus
ArgRS
-
 Rattus norvegicus
RARS
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus ischemic preconditioning can inhibit the increased enzyme activity and down-regulate enzyme expression of ischemia-insulted neurons down
Rattus norvegicus prolonged ischemia insult can induce an escalating activity of the enzyme and leads to enzyme over-expression in primary cultured neurons up