Literature summary for 6.1.1.18 extracted from

Saha, R.; Dasgupta, S.; Banerjee, R.; Mitra-Bhattacharyya, A.; Soell, D.; Basu, G.; Roy, S.
A functional loop spanning distant domains of glutaminyl-tRNA synthetase also stabilizes a molten globule state (2012), Biochemistry, 51, 4429-4437.

Search for more literature for 6.1.1.18

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
D486R/L488Q	the double mutant causes a relaxed tRNA anticodon specificity	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-glutamine + tRNAGln	Escherichia coli	-	AMP + diphosphate + L-glutaminyl-tRNAGln	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P00962	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA agarose column chromatography	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-glutamine + tRNAGln	-	Escherichia coli	AMP + diphosphate + L-glutaminyl-tRNAGln	-	?

Synonyms

Synonyms	Comment	Organism
GlnRS	-	Escherichia coli
Glutaminyl-tRNA synthetase	-	Escherichia coli

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Escherichia coli

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Release 2023.1 (January 2023)