BRENDA - Enzyme Database
show all sequences of 6.1.1.13

D-alanylation of lipoteichoic acid: role of the D-alanyl carrier protein in acylation

Kiriukhin, M.Y.; Neuhaus, F.C.; J. Bacteriol. 183, 2051-2058 (2001)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
ATP + D-alanine + poly(ribitol phosphate)
Lactobacillus casei
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
Lactobacillus casei 102S
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
Lactobacillus casei 102S
r
Organism
Organism
UniProt
Commentary
Textmining
Lactobacillus casei
-
102S
-
Lactobacillus casei 102S
-
102S
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
ATP + D-alanine + poly(ribitol phosphate)
-
651678
Lactobacillus casei
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
651678
Lactobacillus casei
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
r
ATP + D-alanine + poly(ribitol phosphate)
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
651678
Lactobacillus casei 102S
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
r
Synonyms
Synonyms
Commentary
Organism
DCP
-
Lactobacillus casei
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
ATP + D-alanine + poly(ribitol phosphate)
Lactobacillus casei
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
Lactobacillus casei 102S
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
Lactobacillus casei 102S
r
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
ATP + D-alanine + poly(ribitol phosphate)
-
651678
Lactobacillus casei
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
651678
Lactobacillus casei
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei
r
ATP + D-alanine + poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
r
ATP + D-alanine + poly(ribitol phosphate)
the enzyme is required for D-alanylation of membrane-associated lipoteichoic acid in Gram-positive organisms. Dcp has a unique binding site which interacts with the poly(Gro-P) moiety of lipoteichoic acid. The reversibility of this process provides a mechanism for the transacylation of the D-alanyl ester residues between lipoteichoic acids and wall teichoic acids
651678
Lactobacillus casei 102S
AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
-
651678
Lactobacillus casei 102S
r
Other publictions for EC 6.1.1.13
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
726624
Huang
Expression, purification, crys ...
Staphylococcus epidermidis
Acta Crystallogr. Sect. F
68
810-812
2012
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1
1
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727754
Guariglia-Oropeza
Bacillus subtilis delta(V) con ...
Bacillus subtilis 168, Bacillus subtilis
J. Bacteriol.
193
6223-6232
2011
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2
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92
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2
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1
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1
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1
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2
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2
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651678
Kiriukhin
D-alanylation of lipoteichoic ...
Lactobacillus casei 102S, Lactobacillus casei
J. Bacteriol.
183
2051-2058
2001
-
-
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2
-
2
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4
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1
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4
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651652
Debabov
Biosynthesis of lipoteichoic a ...
Lactobacillus rhamnosus, Lactobacillus rhamnosus 7469
J. Bacteriol.
182
2855-2864
2000
1
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2
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6
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4
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1
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1
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4
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210879
Debabov
The D-alanyl carrier protein i ...
Lactobacillus casei
J. Bacteriol.
178
3869-3876
1996
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4
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1
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1
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210877
Perego
Incorporation of D-alanine int ...
Bacillus subtilis
J. Biol. Chem.
270
15598-15606
1995
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3
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1
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1056
Reusch
D-Alanine:membrane acceptor li ...
Lactobacillus casei
J. Biol. Chem.
246
6136-6143
1971
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10
3
3
6
1
1
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10
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3
3
6
1
1
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1
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3
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1
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210876
Baddiley
The enzymic activation of D-al ...
Lactobacillus plantarum
Biochem. J.
75
579-587
1960
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4
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1
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