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Literature summary for 6.1.1.12 extracted from

  • Archontis, G.; Simonson, T.; Moras, D.; Karplus, M.
    Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations (1998), J. Mol. Biol., 275, 823-846.
    View publication on PubMed
Search for more literature for 6.1.1.12

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-aspartate + tRNAAsp Thermus thermophilus specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp Escherichia coli specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp Saccharomyces cerevisiae specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Saccharomyces cerevisiae
-
-
-
Thermus thermophilus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy Thermus thermophilus
a
ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy Saccharomyces cerevisiae
a
ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy, protein-ligand modeling Escherichia coli
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-aspartate + tRNAAsp
-
 Thermus thermophilus AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp
-
 Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp
-
 Saccharomyces cerevisiae AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Thermus thermophilus AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Saccharomyces cerevisiae AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Thermus thermophilus ?
-
 ?
additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Escherichia coli ?
-
 ?
additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
Aspartic acid translase
-
 Thermus thermophilus
Aspartic acid translase
-
 Escherichia coli
Aspartic acid translase
-
 Saccharomyces cerevisiae
Aspartyl ribonucleate synthetase
-
 Thermus thermophilus
Aspartyl ribonucleate synthetase
-
 Escherichia coli
Aspartyl ribonucleate synthetase
-
 Saccharomyces cerevisiae
aspartyl ribonuleic synthetase
-
 Thermus thermophilus
aspartyl ribonuleic synthetase
-
 Escherichia coli
aspartyl ribonuleic synthetase
-
 Saccharomyces cerevisiae
Aspartyl-transfer ribonucleic acid synthetase
-
 Thermus thermophilus
Aspartyl-transfer ribonucleic acid synthetase
-
 Escherichia coli
Aspartyl-transfer ribonucleic acid synthetase
-
 Saccharomyces cerevisiae
Aspartyl-transfer RNA synthetase
-
 Thermus thermophilus
Aspartyl-transfer RNA synthetase
-
 Escherichia coli
Aspartyl-transfer RNA synthetase
-
 Saccharomyces cerevisiae
Aspartyl-tRNA synthetase
-
 Thermus thermophilus
Aspartyl-tRNA synthetase
-
 Escherichia coli
Aspartyl-tRNA synthetase
-
 Saccharomyces cerevisiae