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Literature summary for 6.1.1.10 extracted from

  • Kim, E.Y.; Jung, J.Y.; Kim, A.; Kim, K.; Chang, Y.S.
    Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer (2017), BMC Cancer, 17, 467 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.10

Application

Application Comment Organism
medicine methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + tRNAMet Mus musculus
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet Homo sapiens
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestinal epithelium weak expression Mus musculus
-
kidney marginal expression Mus musculus
-
liver marginal expression Mus musculus
-
lung marginal expression Mus musculus
-
lung marginal expression Homo sapiens
-
non-small cell lung cancer cell high expression Mus musculus
-
non-small cell lung cancer cell high expression Homo sapiens
-
spleen weak expression Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + tRNAMet
-
 Mus musculus AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet
-
 Homo sapiens AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Mus musculus
? x * 100000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
methionyl-tRNA synthetase
-
 Mus musculus
methionyl-tRNA synthetase
-
 Homo sapiens
MRS
-
 Mus musculus
MRS
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus
ATP
-
 Homo sapiens