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Literature summary for 5.6.1.8 extracted from
- Analysis of the ATPase mechanism of myosin subfragment 1 from insect fibrillar flight muscle in the presence and absence of actin, using phosphate-water oxygen exchange measurements (1987), J. Muscle Res. Cell Motil., 8, 537-540.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| actin | - |
Lethocerus indicus |  |
| actin | - |
Lethocerus griseus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + myosin bound to actin filament at position n | Lethocerus indicus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| ATP + H2O + myosin bound to actin filament at position n | Lethocerus griseus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lethocerus griseus | - |
giant waterbug | - |
| Lethocerus indicus | - |
giant waterbug | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibrillar flight muscle | - |
Lethocerus indicus | - |
| fibrillar flight muscle | - |
Lethocerus griseus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + myosin bound to actin filament at position n | - |
Lethocerus indicus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| ATP + H2O + myosin bound to actin filament at position n | - |
Lethocerus griseus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
ATP | basal activity | Lethocerus indicus | |
| 0.03 | - |
ATP | basal activity | Lethocerus griseus | |
| 1.1 | - |
ATP | activation with 0.02 mM actin from rabbit skeletal muscle | Lethocerus indicus | |
| 1.1 | - |
ATP | activation with 0.02 mM actin from rabbit skeletal muscle | Lethocerus griseus | |
| 2.4 | - |
ATP | activation with 0.06 mM actin from rabbit skeletal muscle | Lethocerus indicus | |
| 2.4 | - |
ATP | activation with 0.06 mM actin from rabbit skeletal muscle | Lethocerus griseus | |
| 4.1 | - |
ATP | activation with 0.09 mM actin from rabbit skeletal muscle | Lethocerus indicus | |
| 4.1 | - |
ATP | activation with 0.09 mM actin from rabbit skeletal muscle | Lethocerus griseus | |
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