Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + polypeptide | Mus musculus | - |
ADP + phosphate + unfolded polypeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | O88685 | Rpt5 or 26S protease regulatory subunit 6A | - |
Mus musculus | P54775 | Rpt3 or 26S protease regulatory subunit 6B | - |
Mus musculus | P62192 | Rpt2 or 26S protease regulatory subunit 4 | - |
Mus musculus | P62196 | Rpt6 or 26S protease regulatory subunit 8 | - |
Mus musculus | P62334 | Rpt4 or 26S protease regulatory subunit 10B | - |
Mus musculus | Q8BVQ9 | Rpt1 or 26S protease regulatory subunit 7 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + polypeptide | - |
Mus musculus | ADP + phosphate + unfolded polypeptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
26S protease regulatory subunit 10B | - |
Mus musculus |
26S protease regulatory subunit 4 | - |
Mus musculus |
26S protease regulatory subunit 6A | - |
Mus musculus |
26S protease regulatory subunit 6B | - |
Mus musculus |
26S protease regulatory subunit 7 | - |
Mus musculus |
26S protease regulatory subunit 8 | - |
Mus musculus |
Rpt1 | - |
Mus musculus |
Rpt2 | - |
Mus musculus |
Rpt3 | - |
Mus musculus |
Rpt4 | - |
Mus musculus |
Rpt5 | - |
Mus musculus |
Rpt6 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | in cells deficient for AAA-ATPases of the proteasome 19S regulatory particle, the cholesterol biosynthetic enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase continued to become membrane-extracted, but not cytosolically dislocated | Mus musculus |
physiological function | ATPase of the 19S regulatory particle, RP, subcomplex of the 26S proteasome | Mus musculus |