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Literature summary for 5.6.1.5 extracted from

  • Oberdorf, J.; Carlson, E.J.; Skach, W.R.
    Uncoupling proteasome peptidase and ATPase activities results in cytosolic release of an ER polytopic protein (2006), J. Cell Sci., 119, 303-313.
    View publication on PubMed
Search for more literature for 5.6.1.5

Inhibitors

Inhibitors Comment Organism Structure
hemin inhibitor of proteasome 19S ATPases Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Oryctolagus cuniculus 5829
-
nucleus
-
 Oryctolagus cuniculus 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polypeptide Oryctolagus cuniculus
-
 ADP + phosphate + unfolded polypeptide
-
 ir

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
proteasomes are prepared from rabbit reticulocyte lysates Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
reticulocyte cell-free reticulocyte lysate-based system Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polypeptide
-
 Oryctolagus cuniculus ADP + phosphate + unfolded polypeptide
-
 ir

Synonyms

Synonyms Comment Organism
26S-proteasome
-
 Oryctolagus cuniculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 ATPase activity assay Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 ATPase activity assay Oryctolagus cuniculus