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Literature summary for 5.6.1.1 extracted from

  • Solowska, J.M.; Morfini, G.; Falnikar, A.; Himes, B.T.; Brady, S.T.; Huang, D.; Baas, P.W.
    Quantitative and functional analyses of spastin in the nervous system: implications for hereditary spastic paraplegia (2008), J. Neurosci., 28, 2147-2157.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
additional information high levels of P60-katanin during development Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information dramatically plunge of P60-katanin levels in adult; slightly decline of spastin levels in adult Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 Western blotting, isoform M85 Rattus norvegicus
68000
-
 Western blotting, isoform M1 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebral cortex
-
 Rattus norvegicus
-
cerebral cortical neuron
-
 Rattus norvegicus
-
fibroblast
-
 Rattus norvegicus
-
fibroblast RFL-6 cell Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
heart lower levels of spastin expression compared with neuronal tissues Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
RFL-6 cell
-
 Rattus norvegicus
-
spinal cord
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
P60-katanin
-
 Rattus norvegicus
spastin isoform M1 and isoform M85 Rattus norvegicus