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Literature summary for 5.6.1.1 extracted from
- Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin (2008), Nature, 451, 363-367.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the analysis provides insights into the structural defects in spastin that arise from mutations identified in hereditary paraplegia patients | Drosophila melanogaster |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Drosophila melanogaster |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| the X-ray structure of the nucleotide-free, monomeric AAA domain of Drosophila melanogaster spastin, residues 464-758, is solved at a resolution of 2.7 A | Drosophila melanogaster |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Drosophila melanogaster | - |
ADP + phosphate | - |
ir |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | Q8I0P1 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Drosophila melanogaster |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Drosophila melanogaster | ADP + phosphate | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| hexamer | - |
Drosophila melanogaster |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| spastin | - |
Drosophila melanogaster |
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Release 2023.1 (January 2023)
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