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Literature summary for 5.6.1.1 extracted from

  • Salinas, S.; Carazo-Salas, R.E.; Proukakis, C.; Schiavo, G.; Warner, T.T.
    Spastin and microtubules - Functions in health and disease (2007), J. Neurosci. Res., 85, 2778-2782.
    View publication on PubMed
Search for more literature for 5.6.1.1

Application

Application Comment Organism
medicine spg4, the gene encoding for spastin, is mutated in around 40% of cases of autosomal dominant hereditary spastic paraplegia Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-
membrane
-
 Homo sapiens 16020
-
nucleus
-
 Homo sapiens 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54400
-
 isoform, second ATG, - exon 4 Homo sapiens
58000
-
 isoform, second ATG, + exon 4 Homo sapiens
63600
-
 isoform, first ATG, - exon 4 Homo sapiens
67200
-
 isoform, first ATG, + exon 4 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
 ADP + phosphate
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UBP0
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ir

Synonyms

Synonyms Comment Organism
spastin
-
 Homo sapiens