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Literature summary for 5.6.1.1 extracted from

  • Buster, D.; McNally, K.; McNally, F.J.
    Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis (2002), J. Cell Sci., 115, 1083-1092.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information P-loop substituted mutant of katanin, K-A p60, is a dominant inhibitor of enzyme activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme activity regulates the number of microtubule end in mitotic spindle, enzyme inhibition slows the rate of spindle microtubule disassembly ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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recombinant enzyme expressed by baculoviral system
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme activity regulates the number of microtubule end in mitotic spindle, enzyme inhibition slows the rate of spindle microtubule disassembly Homo sapiens ?
-
?