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Literature summary for 5.5.1.4 extracted from

  • Sipos, L.; Szabo, G.
    Myo-inositol-1-phosphate synthase in different Streptomyces griseus variants (1989), FEMS Microbiol. Lett., 65, 339-344.
    View publication on PubMed
Search for more literature for 5.5.1.4

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.52
-
 glucose 6-phosphate
-
 Streptomyces sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Streptomyces sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
216000
-
 gel filtration Streptomyces sp.

Organism

Organism UniProt Comment Textmining
Streptomyces sp.
-
 Streptomyces griseus
-
Streptomyces sp.
-
 streptomycin producing and streptomycin non-producing strains
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptomyces sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Streptomyces sp.

Storage Stability

Storage Stability Organism
0°C, 70% loss of activity after 18 h, enzyme in crude extract. Stabilization by (NH4)2SO4 and dimethyl sulfoxide in 20% solution Streptomyces sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-Glucose 6-phosphate
-
 Streptomyces sp. L-myo-Inositol 1-phosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45
-
-
 Streptomyces sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.3
-
-
 Streptomyces sp.

Cofactor

Cofactor Comment Organism Structure
NAD+ complete activity without addition of NAD+ Streptomyces sp.