Any feedback?
Literature summary for 5.4.99.7 extracted from
- Overexpression of the homologous lanosterol synthase gene in ganoderic acid biosynthesis in Ganoderma lingzhi (2017), Phytochemistry, 134, 46-53 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| LS gene from Ganoderma lingzhi, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, recombinant overexpression in Ganoderma lucidum, subcloning in Escherichia coli strain JM109, quantitative real-time PCR enzyme expression analysis | Ganoderma lucidum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (3S)-2,3-epoxy-2,3-dihydrosqualene | Ganoderma lucidum | - |
lanosterol | - |
r |  |
| (3S)-2,3-epoxy-2,3-dihydrosqualene | Ganoderma lucidum CGMCC 5.616 | - |
lanosterol | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ganoderma lucidum | A0A1L5JY50 | Ganoderma lucidum strain CGMCC 5.616 is conspecific with Ganoderma lingzhi according to the molecular phylogenetic approach | - |
| Ganoderma lucidum CGMCC 5.616 | A0A1L5JY50 | Ganoderma lucidum strain CGMCC 5.616 is conspecific with Ganoderma lingzhi according to the molecular phylogenetic approach | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mycelium | submerged culture | Ganoderma lucidum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (3S)-2,3-epoxy-2,3-dihydrosqualene | - |
Ganoderma lucidum | lanosterol | - |
r | |
| (3S)-2,3-epoxy-2,3-dihydrosqualene | - |
Ganoderma lucidum CGMCC 5.616 | lanosterol | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 82700, about, sequence calculation | Ganoderma lucidum |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Ganoderma lucidum | sequence calculation | - |
6.26 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | determination of ganoderic acids and lanosterol in mycelia | Ganoderma lucidum |
| physiological function | lanosterol is a common precursor in the biosynthesis of ganoderic acids and ergosterol in Ganoderma lingzhi | Ganoderma lucidum |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
