Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(Z)-3-[4-(4-bromobenzoyl)phenacylidene]quinuclidine | IC50: 83 nM, oral and selective inhibition of cholesterol biosynthesis derived from enzyme inhibition | Homo sapiens | |
(Z)-3-[4-(4-bromobenzoyl)phenacylidene]quinuclidine | IC50: 124 nM, oral and selective inhibition of cholesterol biosynthesis derived from enzyme inhibition | Rattus norvegicus | |
3-[(4-chlorobenzoyl)-4-phenoxy]quinuclidin-3-ol | - |
Homo sapiens | |
3-[(4-chlorobenzoyl)-4-phenoxy]quinuclidin-3-ol | - |
Rattus norvegicus | |
3-[(4-chlorobenzoyl)-4-phenoxy]quinuclidine | - |
Homo sapiens | |
3-[(4-chlorobenzoyl)-4-phenoxy]quinuclidine | - |
Rattus norvegicus | |
3-[2-(4-bromobenzophenone)ethynyl]quinuclidin-3-ol | - |
Homo sapiens | |
3-[2-(4-bromobenzophenone)ethynyl]quinuclidin-3-ol | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
2,3-oxidosqualene cyclase-lanosterol synthase | - |
Homo sapiens |
2,3-oxidosqualene cyclase-lanosterol synthase | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000083 | - |
IC50: 83 nM, oral and selective inhibition of cholesterol biosynthesis derived from enzyme inhibition | Homo sapiens | (Z)-3-[4-(4-bromobenzoyl)phenacylidene]quinuclidine | |
0.000124 | - |
IC50: 124 nM, oral and selective inhibition of cholesterol biosynthesis derived from enzyme inhibition | Rattus norvegicus | (Z)-3-[4-(4-bromobenzoyl)phenacylidene]quinuclidine |