Literature summary for 5.4.99.7 extracted from

Jolidon, S.; Polak, A.M.; Guerry, P.; Hartman, P.G.
Inhibitors of 2,3-oxidosqualene lanosterol-cyclase as potential antifungal agents (1990), Biochem. Soc. Trans., 18, 47-48.

Search for more literature for 5.4.99.7

Inhibitors

Inhibitors	Comment	Organism	Structure
19-Azasqualene	-	Candida albicans
19-Azasqualene	-	Rattus norvegicus
Iminosqualene	-	Candida albicans
Iminosqualene	-	Rattus norvegicus
additional information	antifungal activity of lanosterol synthase inhibitors	Candida albicans
additional information	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Candida albicans	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(S)-squalene-2,3-epoxide	-	Rattus norvegicus	Lanosterol	-	?
(S)-squalene-2,3-epoxide	-	Candida albicans	Lanosterol	-	?

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Release 2023.1 (January 2023)