Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-Phe | - |
Escherichia coli | |
L-Phe | chorismate mutase P is strongly inhibited, chorismate mutase T is not inhibited | Klebsiella aerogenes | |
L-Tyr | - |
Escherichia coli | |
L-Tyr | slight inhibition of chorismate mutase P and no inhibition of chorismate mutase T | Klebsiella aerogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | Escherichia coli | in the biosynthesis of Phe and Tyr, there are two enzymes or enzyme complexes metabolizing chorismate, one leading through prephenate to phenylpyruvate and the other leading through prephenate to 4-hydroxyphenylpyruvate | ? | - |
? | |
Chorismate | Klebsiella aerogenes | in the biosynthesis of Phe and Tyr, there are two enzymes or enzyme complexes metabolizing chorismate, one leading through prephenate to phenylpyruvate and the other leading through prephenate to 4-hydroxyphenylpyruvate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Klebsiella aerogenes | - |
2 enzyme forms: chorismate mutase P and chorismate mutase T. Chorismate mutase P is associated with prephenate dehydratase, chorismate mutase T is associated with prephenate dehydrogenase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | - |
Escherichia coli | Prephenate | - |
? | |
Chorismate | - |
Klebsiella aerogenes | Prephenate | - |
? | |
Chorismate | in the biosynthesis of Phe and Tyr, there are two enzymes or enzyme complexes metabolizing chorismate, one leading through prephenate to phenylpyruvate and the other leading through prephenate to 4-hydroxyphenylpyruvate | Escherichia coli | ? | - |
? | |
Chorismate | in the biosynthesis of Phe and Tyr, there are two enzymes or enzyme complexes metabolizing chorismate, one leading through prephenate to phenylpyruvate and the other leading through prephenate to 4-hydroxyphenylpyruvate | Klebsiella aerogenes | ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
42 | - |
4 min, 59% loss of chorismate mutase P activity, no effect on chorismate mutase T activity | Klebsiella aerogenes |