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Literature summary for 5.4.99.47 extracted from
- Protostadienol synthase from Aspergillus fumigatus: functional conversion into lanosterol synthase (2010), Biochem. Biophys. Res. Commun., 391, 899-902.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Saccharomyces cerevisiae GIL77 cells | Aspergillus fumigatus |
| expressed in Saccharomyces cerevisiae strain GIL77 | Aspergillus fumigatus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus fumigatus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (3S)-2,3-oxidosqualene | - |
Aspergillus fumigatus | lanosterol + parkeol | 1:1 product ratio | ? |  |
| (3S)-2,3-oxidosqualene | - |
Aspergillus fumigatus | parkeol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ERG7 | - |
Aspergillus fumigatus |
| OSLC | - |
Aspergillus fumigatus |
| OSPC | oxidosqualene:protostadienol cyclase mutant in which the residues 702APPGGMR708 are replaced with the conserved 702NKSCAIS708 sequence | Aspergillus fumigatus |
| oxidosqualene:lanosterol cyclase | cf. EC 5.4.99.7 | Aspergillus fumigatus |
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Release 2023.1 (January 2023)
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