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Literature summary for 5.4.99.46 extracted from

  • Sawai, S.; Uchiyama, H.; Mizuno, S.; Aoki, T.; Akashi, T.; Ayabe, S.; Takahashi, T.
    Molecular characterization of an oxidosqualene cyclase that yields shionone, a unique tetracyclic triterpene ketone of Aster tataricus (2011), FEBS Lett., 585, 1031-1036.
    View publication on PubMed
Search for more literature for 5.4.99.46

Cloned(Commentary)

Cloned (Comment) Organism
expressed in lanosterol synthase-deficient yeast Aster tataricus
expressed in Saccharomyces cerevisiae strain GIL77 (lanosterol synthase-deficient strain) Aster tataricus

Organism

Organism UniProt Comment Textmining
Aster tataricus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower
-
 Aster tataricus
-
flower high expression Aster tataricus
-
leaf
-
 Aster tataricus
-
leaf high expression Aster tataricus
-
radical leaf
-
 Aster tataricus
-
rhizome
-
 Aster tataricus
-
root
-
 Aster tataricus
-
stem
-
 Aster tataricus
-
stem high expression Aster tataricus
-
stolon
-
 Aster tataricus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene
-
 Aster tataricus shionone + beta-amyrin + friedelin + dammara-20,24-dienol + 4-epishionone the ratio of the products is roughly estimated as shionone:beta-amyrin:friedelin:dammara-20,24-dienol:4-epishionone = 90%:2%:2%:1.5%:1.5% ?
oxidosqualene
-
 Aster tataricus shionone the cyclase yields ca. 90% shionone and small amounts of beta-amyrin, friedelin, dammara-20,24-dienol, and 4-epishionone ?

Synonyms

Synonyms Comment Organism
OSC
-
 Aster tataricus
Oxidosqualene cyclase
-
 Aster tataricus
shionone synthase
-
 Aster tataricus
SHS
-
 Aster tataricus