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Literature summary for 5.4.99.40 extracted from

  • Brendolise, C.; Yauk, Y.K.; Eberhard, E.D.; Wang, M.; Chagne, D.; Andre, C.; Greenwood, D.R.; Beuning, L.L.
    An unusual plant triterpene synthase with predominant alpha-amyrin-producing activity identified by characterizing oxidosqualene cyclases from Malus × domestica (2011), FEBS J., 278, 2485-2499.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed by transient expression in Nicotiana benthamiana leaves and by expression in the yeast Pichia methanolica Malus domestica
expressed in Nicotiana benthamiana leaves and in Pichia methanolica Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene Malus domestica the product alpha-amyrin is a precursor of ursolic acid alpha-amyrin
-
?

Organism

Organism UniProt Comment Textmining
Malus domestica
-
cultivar Royal Gala
-
Malus domestica C7SCX0 Royal Gala
-

Source Tissue

Source Tissue Comment Organism Textmining
exocarp
-
Malus domestica
-
fruit exocarp Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene the product alpha-amyrin is a precursor of ursolic acid Malus domestica alpha-amyrin
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene the mixed amyrin synthase produces both alpha- and beta-amyrin in a ration of 5:1 Malus domestica alpha-amyrin
-
?
(S)-2,3-oxidosqualene
-
Malus domestica alpha-amyrin + beta-amyrin OSC1 produces a 5:1 ratio of alpha-amyrin to beta-amyrin ?

Synonyms

Synonyms Comment Organism
alpha-amyrin synthase
-
Malus domestica
alpha/beta amyrin synthase
-
Malus domestica
MdOSC1
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Malus domestica
mixed amyrin synthase
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Malus domestica
OSC1 isoform
-
OSC1 isoform Malus domestica
OSC3 isoform
-
OSC3 isoform Malus domestica