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Literature summary for 5.4.99.39 extracted from
- Effect of cation-pi interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of beta-amyrin synthase from Euphorbia tirucalli L (2013), Chemistry, 19, 17150-17158.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| F728A | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| F728H | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| F728I | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| F728M | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| F728W | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| F728Y | activity comparable to wild-type | Euphorbia tirucalli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Euphorbia tirucalli | Q401R6 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-2,3-oxidosqualene | - |
Euphorbia tirucalli | beta-amyrin | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| amyrin synthase | - |
Euphorbia tirucalli |
| EtAS | - |
Euphorbia tirucalli |
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Release 2023.1 (January 2023)
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