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Literature summary for 5.4.99.25 extracted from

  • Hoang, C.; Ferre-D'Amare, A.R.
    Cocrystal structure of a tRNA psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme (2001), Cell, 107, 929-939.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
atomic-resolution crystal structure, TruB bound to RNA at 1.85 A resolution Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P60340
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-

Reaction

Reaction Comment Organism Reaction ID
tRNA uridine55 = tRNA pseudouridine55 this enzyme recognizes the preformed three-dimensional structure of the T loop primarily through shape complementarity. It accesses its substrate uridyl residue by flipping out the nucleotide and disrupts the tertiary structure of tRNA Escherichia coli

Synonyms

Synonyms Comment Organism
TruB
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Escherichia coli