Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cyclopropylcarbonyl-CoA carboxylate | reversible mixed-type inhibition | Homo sapiens | |
methylenecyclopropylacetyl-CoA | reversible mixed-type inhibition | Homo sapiens | |
methylmalonyl-CoA | reversible mixed-type inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.06 | - |
(R/S)-2-methyl-3-oxopropanoyl-CoA | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
expressed in Saccharomyces cerevisiae | - |
Purification (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae | Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
67.4 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-2-methylmalonyl-CoA | - |
Homo sapiens | succinyl-CoA | - |
? | |
(R/S)-2-methyl-3-oxopropanoyl-CoA | - |
Homo sapiens | succinyl-CoA | - |
? | |
ethylmalonyl-CoA | reacts about 1000-10000 times moreslowly than the natural substrate | Homo sapiens | methylsuccinyl-CoA | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
150 | - |
(R/S)-2-methyl-3-oxopropanoyl-CoA | 30°C | Homo sapiens | |
283 | - |
(R/S)-2-methyl-3-oxopropanoyl-CoA | 37°C | Homo sapiens |