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Literature summary for 5.4.3.5 extracted from

  • Wolthers, K.R.; Rigby, S.E.; Scrutton, N.S.
    Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase (2008), J. Biol. Chem., 283, 34615-34625.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain Rosetta(DE3)pLysS Acetoanaerobium sticklandii

Inhibitors

Inhibitors Comment Organism Structure
DL-2,4-diaminobutryic acid
-
Acetoanaerobium sticklandii

Organism

Organism UniProt Comment Textmining
Acetoanaerobium sticklandii
-
strain ATCC 12662
-

Purification (Commentary)

Purification (Comment) Organism
Ni2+ -NTA column chromatography and Q-Sepharose resin chromatography Acetoanaerobium sticklandii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-ornithine
-
Acetoanaerobium sticklandii (2R,4S)-2,4-diaminopentanoate
-
?

Synonyms

Synonyms Comment Organism
OAM
-
Acetoanaerobium sticklandii
ornithine 4,5-aminomutase
-
Acetoanaerobium sticklandii

Cofactor

Cofactor Comment Organism Structure
adenosylcobalamin dependent on Acetoanaerobium sticklandii
pyridoxal 5'-phosphate dependent on Acetoanaerobium sticklandii