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Literature summary for 5.4.3.3 extracted from

  • Stadtman, T.C.; Renz, P.
    Anaerobic degradation of lysine. V. Some properties of the cobamide coenzyme-dependent beta-lysine mutase of Clostridium sticklandii (1968), Arch. Biochem. Biophys., 125, 226-239.
    View publication on PubMed
Search for more literature for 5.4.3.3

Activating Compound

Activating Compound Comment Organism Structure
mercaptan required Acetoanaerobium sticklandii
pyruvate required Acetoanaerobium sticklandii

Inhibitors

Inhibitors Comment Organism Structure
AsO2-
-
 Acetoanaerobium sticklandii
iodoacetamide
-
 Acetoanaerobium sticklandii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.3
-
 3,6-Diaminohexanoate
-
 Acetoanaerobium sticklandii

Metals/Ions

Metals/Ions Comment Organism Structure
K+ monovalent cation required, K+ or Rb+ Acetoanaerobium sticklandii
Mg2+ required Acetoanaerobium sticklandii
Rb+ monovalent cation required, K+ or Rb+ Acetoanaerobium sticklandii

Organism

Organism UniProt Comment Textmining
Acetoanaerobium sticklandii
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Acetoanaerobium sticklandii

Storage Stability

Storage Stability Organism
-18°C, partially purified enzyme in solutions containing phosphate or ammonium sulfate Acetoanaerobium sticklandii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,6-Diaminohexanoate r Acetoanaerobium sticklandii 3,5-Diaminohexanoate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Acetoanaerobium sticklandii

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Acetoanaerobium sticklandii
Cobalamin required as cofactor Acetoanaerobium sticklandii
FAD required Acetoanaerobium sticklandii