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Literature summary for 5.4.2.3 extracted from

  • Macechko, P.T.; Steimle, P.A.; Lindmark, D.G.; Erlandsen, S.L.; Jarroll, E.L.
    Galactosamine-synthesizing enzymes are induced when Giardia encysts (1992), Mol. Biochem. Parasitol., 56, 301-310.
    View publication on PubMed
Search for more literature for 5.4.2.3

Activating Compound

Activating Compound Comment Organism Structure
glucose 1,6-diphosphate required, Km: 0.03 mM Giardia intestinalis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.7
-
 N-acetyl-alpha-D-glucosamine 1-phosphate
-
 Giardia intestinalis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, Km: 1.2 mM Giardia intestinalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-Acetylglucosamine 6-phosphate Giardia intestinalis enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment ?
-
 ?
N-Acetylglucosamine 6-phosphate Giardia intestinalis MR4 enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment ?
-
 ?

Organism

Organism UniProt Comment Textmining
Giardia intestinalis
-
-
-
Giardia intestinalis MR4
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cyst induced during encystment Giardia intestinalis
-
trophozoite
-
 Giardia intestinalis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-alpha-D-glucosamine 1-phosphate
-
 Giardia intestinalis N-acetyl-D-glucosamine 6-phosphate
-
 ?
N-acetyl-alpha-D-glucosamine 1-phosphate
-
 Giardia intestinalis MR4 N-acetyl-D-glucosamine 6-phosphate
-
 ?
N-Acetylglucosamine 6-phosphate enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment Giardia intestinalis ?
-
 ?
N-Acetylglucosamine 6-phosphate enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment Giardia intestinalis MR4 ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Giardia intestinalis