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Literature summary for 5.3.99.5 extracted from

  • Ledergerber, D.; Hartmann, R.W.
    Development of a screening assay for the in vitro evaluation of the thromboxane A2 synthase inhibitors (1995), J. Enzyme Inhib., 9, 253-261.
    View publication on PubMed

Application

Application Comment Organism
pharmacology development of a screening assay for the in vitro evaluation of thromboxane A2 synthase inhibitors. Inhibitors of thromboxane synthase are regarded as potentially useful agents in the treatment of cardiovascular diseases and in the prevention of tumor cell metastases Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information development of a screening assay for the in vitro evaluation of thromboxane A2 synthase inhibitors. Inhibitors of thromboxane synthase are regarded as potentially useful agents in the treatment of cardiovascular diseases and in the prevention of tumor cell metastases Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
platelet
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2 i.e. PGH2 Homo sapiens thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
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