Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.3.99.5 extracted from

  • Haurand, M.; Ullrich, V.
    Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme (1985), J. Biol. Chem., 260, 15059-15067.
    View publication on PubMed
Search for more literature for 5.3.99.5

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58800
-
 x * 58800, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
platelet
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
24.1
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2 i.e. PGH2 Homo sapiens thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
 ?

Subunits

Subunits Comment Organism
? x * 58800, SDS-PAGE Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
27.1
-
 prostaglandin H2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
heme the heme-thiolate group of the enzyme is required to split and activate the endoperoxide bond of prostaglandin H2 Homo sapiens
heme 1 heme per polypeptide chain of MW 58800 Homo sapiens