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Literature summary for 5.3.99.5 extracted from

  • Hall, E.R.; Tuan, W.; Venton, D.L.
    Production of platelet thromboxane A2 inactivates purified human platelet thromboxane synthase (1986), Biochem. J., 233, 637-641.
    View publication on PubMedView publication on EuropePMC

General Stability

General Stability Organism
immobilized enzyme is inactivated at pH 3.0 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
1-Benzylimidazole immobilized enzyme Homo sapiens
Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate immobilized enzyme Homo sapiens
thromboxane A2 the production of thromboxane A2 by the enzyme is self-limiting, the enzyme is inactivated during the reaction Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
platelet
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.259
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2 i.e. PGH2 Homo sapiens thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
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