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Literature summary for 5.3.99.4 extracted from

  • Yeh, H.C.; Gerfen, G.J.; Wang, J.S.; Tsai, A.L.; Wang, L.H.
    Characterization of the peroxidase mechanism upon reaction of prostacyclin synthase with peracetic acid. Identification of a tyrosyl radical intermediate (2009), Biochemistry, 48, 917-928.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
for expression in Escherichia coli cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum membrane
-
 Homo sapiens 5789
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prostaglandin H2 Homo sapiens
-
 prostacyclin
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16647
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin H2
-
 Homo sapiens prostacyclin
-
 ?

Subunits

Subunits Comment Organism
monomer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
CYP8A1
-
 Homo sapiens
PGIS
-
 Homo sapiens
prostacyclin synthase
-
 Homo sapiens
Prostaglandin I2 synthase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
23
-
 kinetic assay Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 kinetic assay Homo sapiens