Literature summary for 5.3.99.4 extracted from

Deng, H.; Huang, A.; So, S.P.; Lin, Y.Z.; Ruan, K.H.
Substrate access channel topology in membrane-bound prostacyclin synthase (2002), Biochem. J., 362, 545-551.

Search for more literature for 5.3.99.4

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Cos-1 cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Homo sapiens	5783	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
57000	-	x * 57000, deduced from nucleotide sequence	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate	Homo sapiens	i.e. prostaglandin H2	(5Z,13E)-(15S)-6,9alpha-epoxy-11a,15-dihydroxyprosta-5,13-dienoate	prostaglandin I2	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate	i.e. prostaglandin H2	Homo sapiens	(5Z,13E)-(15S)-6,9alpha-epoxy-11a,15-dihydroxyprosta-5,13-dienoate	prostaglandin I2	?

Subunits

Subunits	Comment	Organism
?	x * 57000, deduced from nucleotide sequence	Homo sapiens

Synonyms

Synonyms	Comment	Organism
PGIS	-	Homo sapiens
prostacyclin synthase	-	Homo sapiens

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Release 2023.1 (January 2023)