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Literature summary for 5.3.4.1 extracted from

  • Yang, S.; Wang, X.; Cui, L.; Ding, X.; Niu, L.; Yang, F.; Wang, C.; Wang, C.C.; Lou, J.
    Compact conformations of human protein disulfide isomerase (2014), PLoS ONE, 9, e103472 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
D180R/D181R the mutant shows 26.7% of wild type activity Homo sapiens
E431K the mutant shows 53.6% of wild type activity Homo sapiens
K326E the mutant shows 56% of wild type activity Homo sapiens
K326E/E431K the mutant shows 82.2% of wild type activity Homo sapiens
P235G the mutant shows 61.3% of wild type activity Homo sapiens
R97E the mutant shows 68.2% of wild type activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P07237
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin
-
Homo sapiens reduced insulin
-
?

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PDI
-
Homo sapiens
protein disulfide isomerase
-
Homo sapiens