Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Oryza sativa |
Protein Variants | Comment | Organism |
---|---|---|
Cys59/62/195/198Ala | the PDIL2-3 active site mutant is evenly dispersed within the endoplasmic reticulum lumen | Oryza sativa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
rough endoplasmic reticulum | PDIL1-1 is uniformly distributed in the lumen | Oryza sativa | 5791 | - |
rough endoplasmic reticulum | PDIL2-3 is localized mainly on the surface of the endoplasmic reticulum | Oryza sativa | 5791 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
72397 | - |
4 * 72397, PDIL2-3, calculated from amino acid sequence | Oryza sativa |
208000 | - |
PDIL2-3, gel filtration | Oryza sativa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryza sativa | Q53LQ0 | cultivar Kinmaze | - |
Oryza sativa | Q67UF5 | cultivar Kinmaze | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endosperm | - |
Oryza sativa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-globulin | PDIL1-1 facilitates the oxidative folding of alpha-globulin | Oryza sativa | ? | - |
? | |
additional information | PDIL2-3 activity is dispensable in the oxidative folding of alpha-globulin | Oryza sativa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotetramer | 4 * 72397, PDIL2-3, calculated from amino acid sequence | Oryza sativa |
Synonyms | Comment | Organism |
---|---|---|
PDI | - |
Oryza sativa |
PDIL1-1 | - |
Oryza sativa |
PDIL2-3 | - |
Oryza sativa |
protein disulfide isomerase | - |
Oryza sativa |
General Information | Comment | Organism |
---|---|---|
malfunction | PDIL2-3 knockdown causes aberrant accumulation of prolamins in endoplasmic reticulum-derived type-I protein bodies whereas the oxidative folding of vacuole-targeted proteins, such as proglutelins and alpha-globulin, is hardly affected. PDIL2-3 knockdown inhibits the accumulation of Cys-rich 10-kD prolamin in the core of type-I protein bodies | Oryza sativa |
physiological function | PDIL2-3 does not facilitate the oxidative folding of proglutelins | Oryza sativa |
physiological function | the a and a' domains of PDIL1-1 are both functional in the oxidative folding of proglutelins | Oryza sativa |