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Literature summary for 5.3.4.1 extracted from
- Reexamination of the role of interplay between glutathione and protein disulfide isomerase (2011), J. Mol. Biol., 409, 238-249.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-Sepharose column chromatography and Resource Q column chromatography | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDI | - |
Homo sapiens |
| protein disulfide isomerase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | at physiological concentrations of GSSG, the rate-limiting step for the oxidation of the active site of PDI by GSSG is the nucleophilic attack by the C-terminal active-site cysteine on the reduced glutathione (GSH)-PDI mixed disulfide | Homo sapiens |  |
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Release 2023.1 (January 2023)
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