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Literature summary for 5.3.4.1 extracted from

  • Popescu, N.I.; Lupu, C.; Lupu, F.
    Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure (2010), Blood, 116, 993-1001.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
EA.hy926 cell
-
Homo sapiens
-
EAhy 926 cell
-
Homo sapiens
-
endothelial cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PDI
-
Homo sapiens
protein disulfide isomerase
-
Homo sapiens

General Information

General Information Comment Organism
malfunction inhibition of cell surface PDI induces a marked increase in tissue factor procoagulant function Homo sapiens
physiological function extracellular protein disulfide isomerase negatively regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure Homo sapiens