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Literature summary for 5.3.4.1 extracted from

  • Fu, X.M.; Dai, X.; Ding, J.; Zhu, B.T.
    Pancreas-specific protein disulfide isomerase has a cell type-specific expression in various mouse tissues and is absent in human pancreatic adenocarcinoma cells: implications for its functions (2009), J. Mol. Histol., 40, 189-199.
    View publication on PubMed

Application

Application Comment Organism
diagnostics the absence of PDIp expression in pancreatic adenocarcinoma may serve as an additional biomarker for pancreatic cancer Mus musculus
diagnostics the absence of PDIp expression in pancreatic adenocarcinoma may serve as an additional biomarker for pancreatic cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
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Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
epididymis low expression level of PDIp Mus musculus
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ileum PDIp is exclusively expressed in Paneth cells Mus musculus
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kidney
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Mus musculus
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liver low expression level of PDIp Mus musculus
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lung
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Mus musculus
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additional information no activity of PDIp in pancreatic adenocarcinoma cells Homo sapiens
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additional information no or poor expression of PDIp in colon, cecum, and duodenum. PDIp shows a cell-type specific expression in various mouse tissues, in the digestive organs, such as the stomach and pancreas, very high levels of PDIp are selectively expressed in the digestive enzyme-secreting cells Mus musculus
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pancreas
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Homo sapiens
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pancreas pancreas-specific protein disulfide isomerase, PDIp, specific expression in pancreatic acinar cells, high expression level of PDIp Mus musculus
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spleen low expression level of PDIp Mus musculus
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stomach specific expression of PDIp in gastric chief cells, high expression level of PDIp Mus musculus
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uterus high expression level of PDIp Mus musculus
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Synonyms

Synonyms Comment Organism
pancreas-specific protein disulfide isomerase
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Mus musculus
pancreas-specific protein disulfide isomerase
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Homo sapiens
PDIp
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Mus musculus
PDIp
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Homo sapiens

General Information

General Information Comment Organism
physiological function PDIp may function as a protein-folding catalyst for secretory digestive enzymes Mus musculus