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Literature summary for 5.3.4.1 extracted from
- Identification and enzymatic activities of four protein disulfide isomerase (PDI) isoforms of Leishmania amazonensis (2007), Parasitol. Res., 102, 437-446.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cCMP | - |
Leishmania amazonensis |  |
| GSH | - |
Leishmania amazonensis | |
| GSSG | - |
Leishmania amazonensis | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| isozyme pdi-15, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| isozyme pdi-40, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| isozyme pdi-47, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| isozyme pdi-52, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-chloromercuribenzoic acid | - |
Leishmania amazonensis | |
| bacitracin | - |
Leishmania amazonensis | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | kinetics | Leishmania amazonensis |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 15000 | - |
x * 15000, isozyme pdi-15, SDS-PAGE | Leishmania amazonensis |
| 40000 | - |
x * 40000, isozyme pdi-40, SDS-PAGE | Leishmania amazonensis |
| 47000 | - |
x * 47000, isozyme pdi-47, SDS-PAGE | Leishmania amazonensis |
| 52000 | - |
x * 52000, isozyme pdi-52, SDS-PAGE | Leishmania amazonensis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania amazonensis | A7YBW7 | 52 kDa isozyme | - |
| Leishmania amazonensis | A7YBX0 | 47 kDa isozyme, fragment | - |
| Leishmania amazonensis | A7YBX2 | 40 kDa isozyme, fragment | - |
| Leishmania amazonensis | A7YBX4 | 15 kDa isozyme, fragment | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| insulin | - |
Leishmania amazonensis | ? | - |
? | |
| scrambled RNAse | - |
Leishmania amazonensis | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 15000, isozyme pdi-15, SDS-PAGE | Leishmania amazonensis |
| ? | x * 40000, isozyme pdi-40, SDS-PAGE | Leishmania amazonensis |
| ? | x * 47000, isozyme pdi-47, SDS-PAGE | Leishmania amazonensis |
| ? | x * 52000, isozyme pdi-52, SDS-PAGE | Leishmania amazonensis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDI | - |
Leishmania amazonensis |
| pdi-15 | - |
Leishmania amazonensis |
| pdi-40 | - |
Leishmania amazonensis |
| pdi-47 | - |
Leishmania amazonensis |
| pdi-52 | - |
Leishmania amazonensis |
| protein-disulfide isomerase | - |
Leishmania amazonensis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Leishmania amazonensis |
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Release 2023.1 (January 2023)
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