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Literature summary for 5.3.4.1 extracted from

  • Freedman, R.B.; Hawkins, H.C.; Murant, S.J.; Reid, L.
    Protein disulphide-isomerase: a homologue of thioredixin implicated in the biosynthesis of secretory proteins (1988), Biochem. Soc. Trans., 16, 96-99.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide
-
Bos taurus
iodoacetamide
-
Homo sapiens
iodoacetamide
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Proteins Homo sapiens native, reduced or with wrong disulfide bonds ?
-
?
Proteins Rattus norvegicus native, reduced or with wrong disulfide bonds ?
-
?
Proteins Bos taurus native, reduced or with wrong disulfide bonds ?
-
?
Proteins Homo sapiens implicated in the biosynthesis of secretory proteins ?
-
?
Proteins Rattus norvegicus implicated in the biosynthesis of secretory proteins ?
-
?
Proteins Bos taurus implicated in the biosynthesis of secretory proteins ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
catalyses the rearrangement of -S-S- bonds in proteins mechanism Homo sapiens
catalyses the rearrangement of -S-S- bonds in proteins mechanism Rattus norvegicus
catalyses the rearrangement of -S-S- bonds in proteins mechanism Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Proteins native, reduced or with wrong disulfide bonds Homo sapiens Proteins with correct disulfide bonds ?
Proteins native, reduced or with wrong disulfide bonds Rattus norvegicus Proteins with correct disulfide bonds ?
Proteins native, reduced or with wrong disulfide bonds Bos taurus Proteins with correct disulfide bonds ?
Proteins native, reduced or with wrong disulfide bonds Homo sapiens ?
-
?
Proteins native, reduced or with wrong disulfide bonds Rattus norvegicus ?
-
?
Proteins native, reduced or with wrong disulfide bonds Bos taurus ?
-
?
Proteins implicated in the biosynthesis of secretory proteins Homo sapiens ?
-
?
Proteins implicated in the biosynthesis of secretory proteins Rattus norvegicus ?
-
?
Proteins implicated in the biosynthesis of secretory proteins Bos taurus ?
-
?