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Literature summary for 5.3.3.1 extracted from

  • Aste, N.; Watanabe, Y.; Shimada, K.; Saito, N.
    Sex- and age-related variation in neurosteroidogenic enzyme mRNA levels during quail embryonic development (2008), Brain Res., 1201, 15-22.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Coturnix japonica
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Source Tissue

Source Tissue Comment Organism Textmining
prosencephalon of embryo. Levels of bifunctional 3beta-hydroxysteroid-dehydrogenase/DELTA4-DELTA5-isomerase are sexually dimorphic and developmental age-dependent. MRNA levels are higher in females than in males at E7, whereas this dimorphism is reversed at E9 and E15. In females, the highest mRNA level is at E7, whereas in males the levels are significantly higher at E9 and E17 than at E7 and E11. Sexual dimorphism can only be detcted in prosencephalon, can not be observed before gonadal sexual differentiation, and is not paralleled by a dimorphism in brain content of progesterone Coturnix japonica
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