Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
melanoma cell | - |
Homo sapiens | - |
SB-2 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AMF | - |
Homo sapiens |
phosphoglucose isomerase/autocrine motility factor | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | key enzyme in the AMF signaling pathway, overview | Homo sapiens |
physiological function | AMF is critical for the migration, invasion, metastasis, and anti-apoptotic effects of malignant tumor cells, and its multiple roles in tumor progression may be mediated by certain downstream pathways and effectors. Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8, overview | Homo sapiens |