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Literature summary for 5.3.1.9 extracted from

  • Araki, K.; Shimura, T.; Yajima, T.; Tsutsumi, S.; Suzuki, H.; Okada, K.; Kobayashi, T.; Raz, A.; Kuwano, H.
    Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8 (2009), J. Biol. Chem., 284, 32305-32311.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell
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Homo sapiens
-
SB-2 cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
AMF
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Homo sapiens
phosphoglucose isomerase/autocrine motility factor
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Homo sapiens

General Information

General Information Comment Organism
metabolism key enzyme in the AMF signaling pathway, overview Homo sapiens
physiological function AMF is critical for the migration, invasion, metastasis, and anti-apoptotic effects of malignant tumor cells, and its multiple roles in tumor progression may be mediated by certain downstream pathways and effectors. Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8, overview Homo sapiens