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Literature summary for 5.3.1.9 extracted from
- Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes (2010), J. Antimicrob. Chemother., 65, 512-519.
Application
| Application | Comment | Organism |
|---|---|---|
| drug development | the enzyme is a target for development of specific inhibitors against Echinococcus multilocularismetacestodes and disease alveolar echinococcosis, overview | Echinococcus multilocularis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | screening for thiazolide inhibitors, diverse compounds, mode of action of thiazolides and structure-activity relationship, overview | Echinococcus multilocularis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Echinococcus multilocularis | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| metacestode | PGI activity in vesicle fluid | Echinococcus multilocularis | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGI | - |
Echinococcus multilocularis |
| Phosphoglucose isomerase | - |
Echinococcus multilocularis |
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