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Literature summary for 5.3.1.6 extracted from
- Ribose 5-phosphate isomerase inhibits LC3 processing and basal autophagy (2016), Cell. Signal., 28, 1380-1388 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P49247 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RpiA | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | knockdown or genomic deletion of RPIA results in an increase of ATG4B proteases-mediated processing of autosome marker protein LC3 and in the appearance of LC3-positive autophagosomes in cells. Increased LC3 processing upon knockdown of RPIA can be reversed by treatment with N-acetyl cysteine | Homo sapiens |
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Release 2023.1 (January 2023)
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