Literature summary for 5.3.1.6 extracted from

Burgos, E.; Roos, A.K.; Mowbray, S.L.; Salmon, L.
Synthesis of 5-deoxy-5-phospho-D-ribonohydroxamic acid: a new competitive and selective inhibitor of type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis (2005), Tetrahedron Lett., 46, 3691-3694.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
5-deoxy-5-phospho-D-ribonohydroxamic acid	competitive and selective inhibitor of type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis	Mycobacterium tuberculosis
5-deoxy-5-phospho-D-ribonohydroxamic acid	weak	Spinacia oleracea

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	-	-	-
Spinacia oleracea	-	-	-

Synonyms

Synonyms	Comment	Organism
RpiB	-	Spinacia oleracea
RpiB	-	Mycobacterium tuberculosis
type B ribose-5-phosphate isomerase	-	Spinacia oleracea
type B ribose-5-phosphate isomerase	-	Mycobacterium tuberculosis

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.4	-	5-deoxy-5-phospho-D-ribonohydroxamic acid	-	Mycobacterium tuberculosis
6.2	-	5-deoxy-5-phospho-D-ribonohydroxamic acid	-	Spinacia oleracea

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Release 2023.1 (January 2023)