Literature summary for 5.3.1.5 extracted from

Kovalevsky, A.Y.; Hanson, L.; Fisher, S.Z.; Mustyakimov, M.; Mason, S.A.; Forsyth, V.T.; Blakeley, M.P.; Keen, D.A.; Wagner, T.; Carrell, H.L.; Katz, A.K.; Glusker, J.P.; Langan, P.
Metal ion roles and the movement of hydrogen during reaction catalyzed by D-xylose isomerase: a joint x-ray and neutron diffraction study (2010), Structure, 18, 688-699.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Al3+	-	Streptomyces rubiginosus
Ba2+	-	Streptomyces rubiginosus
Ca2+	-	Streptomyces rubiginosus
Cd2+	-	Streptomyces rubiginosus
Cu2+	-	Streptomyces rubiginosus
Fe3+	-	Streptomyces rubiginosus
Hg2+	-	Streptomyces rubiginosus
Ni2+	-	Streptomyces rubiginosus
Pb2+	-	Streptomyces rubiginosus
Sr2+	-	Streptomyces rubiginosus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Co2+	activates	Streptomyces rubiginosus
Fe2+	activates	Streptomyces rubiginosus
Mg2+	activates	Streptomyces rubiginosus
Mn2+	activates	Streptomyces rubiginosus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-Xylose	Streptomyces rubiginosus	-	D-Xylulose	-	r

Organism

Organism	UniProt	Comment	Textmining
Streptomyces rubiginosus	P24300	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
alpha-D-glucose	-	Streptomyces rubiginosus	alpha-D-fructose	-	r
D-Xylose	-	Streptomyces rubiginosus	D-Xylulose	-	r

Subunits

Subunits	Comment	Organism
homotetramer	x-ray crystallography	Streptomyces rubiginosus

Synonyms

Synonyms	Comment	Organism
D-xylose isomerase	-	Streptomyces rubiginosus

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Release 2023.1 (January 2023)